cardiac contractility Search Results


rapid in vitro and in vivo phosphorylation of phospholamban by cardiac contractility modulation electrical signals  (Impulse Dynamics USA Inc)
90
Impulse Dynamics USA Inc rapid in vitro and in vivo phosphorylation of phospholamban by cardiac contractility modulation electrical signals
Rapid In Vitro And In Vivo Phosphorylation Of Phospholamban By Cardiac Contractility Modulation Electrical Signals, supplied by Impulse Dynamics USA Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cardiac+contractility/10__1016_slash_j__jacc__2009__01__015-2654-5-37?v=Impulse+Dynamics+USA+Inc
Average 90 stars, based on 1 article reviews
rapid in vitro and in vivo phosphorylation of phospholamban by cardiac contractility modulation electrical signals - by Bioz Stars, 2026-08
90/100 stars
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mouse cardiac structure and contractility imaging  (FUJIFILM VisualSonics Inc)
90
FUJIFILM VisualSonics Inc mouse cardiac structure and contractility imaging
Mouse Cardiac Structure And Contractility Imaging, supplied by FUJIFILM VisualSonics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cardiac+contractility/pmc05931234-187-4-8?v=FUJIFILM+VisualSonics+Inc
Average 90 stars, based on 1 article reviews
mouse cardiac structure and contractility imaging - by Bioz Stars, 2026-08
90/100 stars
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cardiac contractility  (Pfleger GmbH)
90
Pfleger GmbH cardiac contractility
Cardiac Contractility, supplied by Pfleger GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cardiac+contractility/10__1017_slash_s0954579420001613-176-8-12?v=Pfleger+GmbH
Average 90 stars, based on 1 article reviews
cardiac contractility - by Bioz Stars, 2026-08
90/100 stars
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cardiac contractility modulation therapy  (CardioMEMS Inc)
90
CardioMEMS Inc cardiac contractility modulation therapy
Cardiac Contractility Modulation Therapy, supplied by CardioMEMS Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cardiac+contractility/pm39243517-341-32-41?v=CardioMEMS+Inc
Average 90 stars, based on 1 article reviews
cardiac contractility modulation therapy - by Bioz Stars, 2026-08
90/100 stars
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cardiac contractility measurement  (IonOptix)
90
IonOptix cardiac contractility measurement
IGBP1P1 is vital in cell size and <t>contractility</t> in human cardiac tissue mimetics. A Relative mRNA expression of RP11-98F14.11, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM RP11-98F14.11 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. B Relative mRNA expression of RPL23AP92, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 were detected. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. C Relative mRNA expression of IGBP1P1, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. D Representative images of α-actinin (red) and DAPI (blue) in 40-day-old human MCOs after GM IGBP1P1 or the GM Ctrl in normoxia or hypoxia for 3 days. Scale bar is 50 µm. E Cardiomyocyte cell size in the MCOs was assessed by the Image J. 50 cells were analyzed for each condition. Data are represented as Mean ± SEM; n = 3; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. F Human MCOs were treated with GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia for 3 days, and then the frequency of CMO contraction was determined by counting beats per minute. Data are represented as Mean ± SEM; 4–5 organoids per group; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. G Representative traces of contractile MCOs. H The contractility assays were performed by determining the amplitude peak of contracting MCOs. Data are represented as Mean ± SEM; 4–5 organoids per group; * P < 0.05 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. All by one-way ANOVA analyses followed by a Dunnett’s multiple comparison post-test. MCOs, monoculture cardiac organoids
Cardiac Contractility Measurement, supplied by IonOptix, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cardiac+contractility/pmc10369730-337-5-11?v=IonOptix
Average 90 stars, based on 1 article reviews
cardiac contractility measurement - by Bioz Stars, 2026-08
90/100 stars
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cardiac contractility modulation optimizer smart  (Impulse Dynamics USA Inc)
90
Impulse Dynamics USA Inc cardiac contractility modulation optimizer smart
IGBP1P1 is vital in cell size and <t>contractility</t> in human cardiac tissue mimetics. A Relative mRNA expression of RP11-98F14.11, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM RP11-98F14.11 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. B Relative mRNA expression of RPL23AP92, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 were detected. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. C Relative mRNA expression of IGBP1P1, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. D Representative images of α-actinin (red) and DAPI (blue) in 40-day-old human MCOs after GM IGBP1P1 or the GM Ctrl in normoxia or hypoxia for 3 days. Scale bar is 50 µm. E Cardiomyocyte cell size in the MCOs was assessed by the Image J. 50 cells were analyzed for each condition. Data are represented as Mean ± SEM; n = 3; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. F Human MCOs were treated with GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia for 3 days, and then the frequency of CMO contraction was determined by counting beats per minute. Data are represented as Mean ± SEM; 4–5 organoids per group; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. G Representative traces of contractile MCOs. H The contractility assays were performed by determining the amplitude peak of contracting MCOs. Data are represented as Mean ± SEM; 4–5 organoids per group; * P < 0.05 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. All by one-way ANOVA analyses followed by a Dunnett’s multiple comparison post-test. MCOs, monoculture cardiac organoids
Cardiac Contractility Modulation Optimizer Smart, supplied by Impulse Dynamics USA Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cardiac+contractility/pmc11050600-163-40-50?v=Impulse+Dynamics+USA+Inc
Average 90 stars, based on 1 article reviews
cardiac contractility modulation optimizer smart - by Bioz Stars, 2026-08
90/100 stars
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cardiac contractility sensor  (MicroPort Scientific Corporation)
90
MicroPort Scientific Corporation cardiac contractility sensor
IGBP1P1 is vital in cell size and <t>contractility</t> in human cardiac tissue mimetics. A Relative mRNA expression of RP11-98F14.11, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM RP11-98F14.11 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. B Relative mRNA expression of RPL23AP92, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 were detected. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. C Relative mRNA expression of IGBP1P1, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. D Representative images of α-actinin (red) and DAPI (blue) in 40-day-old human MCOs after GM IGBP1P1 or the GM Ctrl in normoxia or hypoxia for 3 days. Scale bar is 50 µm. E Cardiomyocyte cell size in the MCOs was assessed by the Image J. 50 cells were analyzed for each condition. Data are represented as Mean ± SEM; n = 3; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. F Human MCOs were treated with GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia for 3 days, and then the frequency of CMO contraction was determined by counting beats per minute. Data are represented as Mean ± SEM; 4–5 organoids per group; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. G Representative traces of contractile MCOs. H The contractility assays were performed by determining the amplitude peak of contracting MCOs. Data are represented as Mean ± SEM; 4–5 organoids per group; * P < 0.05 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. All by one-way ANOVA analyses followed by a Dunnett’s multiple comparison post-test. MCOs, monoculture cardiac organoids
Cardiac Contractility Sensor, supplied by MicroPort Scientific Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cardiac+contractility/pmc06733485-58-13-21?v=MicroPort+Scientific+Corporation
Average 90 stars, based on 1 article reviews
cardiac contractility sensor - by Bioz Stars, 2026-08
90/100 stars
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conductivity-dependent improvements in nanowired cardiac microtissue contractility  (Nanowired gmbh)
90
Nanowired gmbh conductivity-dependent improvements in nanowired cardiac microtissue contractility
IGBP1P1 is vital in cell size and <t>contractility</t> in human cardiac tissue mimetics. A Relative mRNA expression of RP11-98F14.11, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM RP11-98F14.11 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. B Relative mRNA expression of RPL23AP92, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 were detected. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. C Relative mRNA expression of IGBP1P1, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. D Representative images of α-actinin (red) and DAPI (blue) in 40-day-old human MCOs after GM IGBP1P1 or the GM Ctrl in normoxia or hypoxia for 3 days. Scale bar is 50 µm. E Cardiomyocyte cell size in the MCOs was assessed by the Image J. 50 cells were analyzed for each condition. Data are represented as Mean ± SEM; n = 3; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. F Human MCOs were treated with GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia for 3 days, and then the frequency of CMO contraction was determined by counting beats per minute. Data are represented as Mean ± SEM; 4–5 organoids per group; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. G Representative traces of contractile MCOs. H The contractility assays were performed by determining the amplitude peak of contracting MCOs. Data are represented as Mean ± SEM; 4–5 organoids per group; * P < 0.05 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. All by one-way ANOVA analyses followed by a Dunnett’s multiple comparison post-test. MCOs, monoculture cardiac organoids
Conductivity Dependent Improvements In Nanowired Cardiac Microtissue Contractility, supplied by Nanowired gmbh, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cardiac+contractility/pmc10403216__sciadv__adf2898_sm-36-0-3?v=Nanowired+gmbh
Average 90 stars, based on 1 article reviews
conductivity-dependent improvements in nanowired cardiac microtissue contractility - by Bioz Stars, 2026-08
90/100 stars
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cardiac contractility sensor indirectly  (Biotronik GmbH)
90
Biotronik GmbH cardiac contractility sensor indirectly
IGBP1P1 is vital in cell size and <t>contractility</t> in human cardiac tissue mimetics. A Relative mRNA expression of RP11-98F14.11, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM RP11-98F14.11 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. B Relative mRNA expression of RPL23AP92, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 were detected. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. C Relative mRNA expression of IGBP1P1, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. D Representative images of α-actinin (red) and DAPI (blue) in 40-day-old human MCOs after GM IGBP1P1 or the GM Ctrl in normoxia or hypoxia for 3 days. Scale bar is 50 µm. E Cardiomyocyte cell size in the MCOs was assessed by the Image J. 50 cells were analyzed for each condition. Data are represented as Mean ± SEM; n = 3; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. F Human MCOs were treated with GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia for 3 days, and then the frequency of CMO contraction was determined by counting beats per minute. Data are represented as Mean ± SEM; 4–5 organoids per group; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. G Representative traces of contractile MCOs. H The contractility assays were performed by determining the amplitude peak of contracting MCOs. Data are represented as Mean ± SEM; 4–5 organoids per group; * P < 0.05 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. All by one-way ANOVA analyses followed by a Dunnett’s multiple comparison post-test. MCOs, monoculture cardiac organoids
Cardiac Contractility Sensor Indirectly, supplied by Biotronik GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cardiac+contractility/pm11333049-85-18-19?v=Biotronik+GmbH
Average 90 stars, based on 1 article reviews
cardiac contractility sensor indirectly - by Bioz Stars, 2026-08
90/100 stars
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measurement of sarcomere lengths as a surrogate for cardiac contractility  (IonOptix)
90
IonOptix measurement of sarcomere lengths as a surrogate for cardiac contractility
IGBP1P1 is vital in cell size and <t>contractility</t> in human cardiac tissue mimetics. A Relative mRNA expression of RP11-98F14.11, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM RP11-98F14.11 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. B Relative mRNA expression of RPL23AP92, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 were detected. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. C Relative mRNA expression of IGBP1P1, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. D Representative images of α-actinin (red) and DAPI (blue) in 40-day-old human MCOs after GM IGBP1P1 or the GM Ctrl in normoxia or hypoxia for 3 days. Scale bar is 50 µm. E Cardiomyocyte cell size in the MCOs was assessed by the Image J. 50 cells were analyzed for each condition. Data are represented as Mean ± SEM; n = 3; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. F Human MCOs were treated with GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia for 3 days, and then the frequency of CMO contraction was determined by counting beats per minute. Data are represented as Mean ± SEM; 4–5 organoids per group; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. G Representative traces of contractile MCOs. H The contractility assays were performed by determining the amplitude peak of contracting MCOs. Data are represented as Mean ± SEM; 4–5 organoids per group; * P < 0.05 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. All by one-way ANOVA analyses followed by a Dunnett’s multiple comparison post-test. MCOs, monoculture cardiac organoids
Measurement Of Sarcomere Lengths As A Surrogate For Cardiac Contractility, supplied by IonOptix, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cardiac+contractility/pmc04376763-176-10-3?v=IonOptix
Average 90 stars, based on 1 article reviews
measurement of sarcomere lengths as a surrogate for cardiac contractility - by Bioz Stars, 2026-08
90/100 stars
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cardiac contractility modulation (ccm; optimizer smart)  (Impulse Dynamics USA Inc)
90
Impulse Dynamics USA Inc cardiac contractility modulation (ccm; optimizer smart)
IGBP1P1 is vital in cell size and <t>contractility</t> in human cardiac tissue mimetics. A Relative mRNA expression of RP11-98F14.11, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM RP11-98F14.11 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. B Relative mRNA expression of RPL23AP92, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 were detected. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. C Relative mRNA expression of IGBP1P1, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. D Representative images of α-actinin (red) and DAPI (blue) in 40-day-old human MCOs after GM IGBP1P1 or the GM Ctrl in normoxia or hypoxia for 3 days. Scale bar is 50 µm. E Cardiomyocyte cell size in the MCOs was assessed by the Image J. 50 cells were analyzed for each condition. Data are represented as Mean ± SEM; n = 3; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. F Human MCOs were treated with GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia for 3 days, and then the frequency of CMO contraction was determined by counting beats per minute. Data are represented as Mean ± SEM; 4–5 organoids per group; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. G Representative traces of contractile MCOs. H The contractility assays were performed by determining the amplitude peak of contracting MCOs. Data are represented as Mean ± SEM; 4–5 organoids per group; * P < 0.05 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. All by one-way ANOVA analyses followed by a Dunnett’s multiple comparison post-test. MCOs, monoculture cardiac organoids
Cardiac Contractility Modulation (Ccm; Optimizer Smart), supplied by Impulse Dynamics USA Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cardiac+contractility/pm38667743-300-39-48?v=Impulse+Dynamics+USA+Inc
Average 90 stars, based on 1 article reviews
cardiac contractility modulation (ccm; optimizer smart) - by Bioz Stars, 2026-08
90/100 stars
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cardiac contractility  (IonOptix)
90
IonOptix cardiac contractility
IGBP1P1 is vital in cell size and <t>contractility</t> in human cardiac tissue mimetics. A Relative mRNA expression of RP11-98F14.11, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM RP11-98F14.11 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. B Relative mRNA expression of RPL23AP92, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 were detected. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. C Relative mRNA expression of IGBP1P1, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. D Representative images of α-actinin (red) and DAPI (blue) in 40-day-old human MCOs after GM IGBP1P1 or the GM Ctrl in normoxia or hypoxia for 3 days. Scale bar is 50 µm. E Cardiomyocyte cell size in the MCOs was assessed by the Image J. 50 cells were analyzed for each condition. Data are represented as Mean ± SEM; n = 3; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. F Human MCOs were treated with GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia for 3 days, and then the frequency of CMO contraction was determined by counting beats per minute. Data are represented as Mean ± SEM; 4–5 organoids per group; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. G Representative traces of contractile MCOs. H The contractility assays were performed by determining the amplitude peak of contracting MCOs. Data are represented as Mean ± SEM; 4–5 organoids per group; * P < 0.05 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. All by one-way ANOVA analyses followed by a Dunnett’s multiple comparison post-test. MCOs, monoculture cardiac organoids
Cardiac Contractility, supplied by IonOptix, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cardiac+contractility/10__1016_slash_j__vascn__2023__107267-1105-8-10?v=IonOptix
Average 90 stars, based on 1 article reviews
cardiac contractility - by Bioz Stars, 2026-08
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Image Search Results


IGBP1P1 is vital in cell size and contractility in human cardiac tissue mimetics. A Relative mRNA expression of RP11-98F14.11, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM RP11-98F14.11 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. B Relative mRNA expression of RPL23AP92, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 were detected. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. C Relative mRNA expression of IGBP1P1, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. D Representative images of α-actinin (red) and DAPI (blue) in 40-day-old human MCOs after GM IGBP1P1 or the GM Ctrl in normoxia or hypoxia for 3 days. Scale bar is 50 µm. E Cardiomyocyte cell size in the MCOs was assessed by the Image J. 50 cells were analyzed for each condition. Data are represented as Mean ± SEM; n = 3; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. F Human MCOs were treated with GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia for 3 days, and then the frequency of CMO contraction was determined by counting beats per minute. Data are represented as Mean ± SEM; 4–5 organoids per group; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. G Representative traces of contractile MCOs. H The contractility assays were performed by determining the amplitude peak of contracting MCOs. Data are represented as Mean ± SEM; 4–5 organoids per group; * P < 0.05 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. All by one-way ANOVA analyses followed by a Dunnett’s multiple comparison post-test. MCOs, monoculture cardiac organoids

Journal: Human Genomics

Article Title: CVD-associated SNPs with regulatory potential reveal novel non-coding disease genes

doi: 10.1186/s40246-023-00513-4

Figure Lengend Snippet: IGBP1P1 is vital in cell size and contractility in human cardiac tissue mimetics. A Relative mRNA expression of RP11-98F14.11, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM RP11-98F14.11 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. B Relative mRNA expression of RPL23AP92, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 were detected. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. C Relative mRNA expression of IGBP1P1, COL3A1, MMP2, TGFb1, NPPA, NPPB, MYH7 and ratio MYH7/6 in MCOs transduced with either GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia. Data are represented as Mean ± SEM; n = 3; * P < 0.05, ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. D Representative images of α-actinin (red) and DAPI (blue) in 40-day-old human MCOs after GM IGBP1P1 or the GM Ctrl in normoxia or hypoxia for 3 days. Scale bar is 50 µm. E Cardiomyocyte cell size in the MCOs was assessed by the Image J. 50 cells were analyzed for each condition. Data are represented as Mean ± SEM; n = 3; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. F Human MCOs were treated with GM IGBP1P1 or GM Ctrl in both normoxia and hypoxia for 3 days, and then the frequency of CMO contraction was determined by counting beats per minute. Data are represented as Mean ± SEM; 4–5 organoids per group; ** P < 0.01 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. G Representative traces of contractile MCOs. H The contractility assays were performed by determining the amplitude peak of contracting MCOs. Data are represented as Mean ± SEM; 4–5 organoids per group; * P < 0.05 vs. Normoxia GM Ctrl, % P < 0.05 vs. Hypoxia GM Ctrl. All by one-way ANOVA analyses followed by a Dunnett’s multiple comparison post-test. MCOs, monoculture cardiac organoids

Article Snippet: MCOs, monoculture cardiac organoids Furthermore, cardiac contractility was also measured by IonOptix and through calcium flux analysis.

Techniques: Expressing, Transduction, Comparison